HRT, Endocrinology, and Health
IMPORTANT: These resources are presented WITHOUT WARRANTY or PROMISE or MEDICAL RECOMMENDATION of any kind, expressed or implied! Read and make your own decisions; feel free to ask someone else in the community about the information you find. Consult your health care provider, but also be informed -- sometimes providers don't have access to the latest information, so you might want to search the Internet for updates to the following.
Please send me additions, updates, and corrections to this list! Thanks.
General
- WPATH World Professional Association for Transgender Health
Standards of Care Version 8 - International Journal of Transgender Health (some articles cost $)
Plucked from our Discord Server
- An Introduction to Hormone Therapy for Transfeminine People - Transfeminine Science -- Somewhat mimicking the style of a scientific study, this is a pretty good introduction - but also you should read actual peer-reviewed articles on NIH
- DIY HRT (use at your own risk - be sure to buy bioidentical pharmaceutical grade products!) - https://diyhrt.wiki/transfem
- The case against spironolactone - https://moderntranshormones.com/2018/01/01/02/39/56/whats-wrong-with-spironolactone/
- A good article from Pink News - https://www.thepinknews.com/2025/11/12/hrt-trans-women-study-feminising-hormones/
- DIY HRT video: "Everything I Can Legally Tell You" - https://www.youtube.com/watch?v=o2Ggwe2j0Gc
- About cycling progesterone - https://pubmed.ncbi.nlm.nih.gov/39597939/
- Anti-androgen therapy - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366074/
- Breast Imaging - https://pmc.ncbi.nlm.nih.gov/articles/PMC5773616/
- Breast development - https://pmc.ncbi.nlm.nih.gov/articles/PMC8664122/
- Breast growth options - https://www.folxhealth.com/library/estrogen-hrt-breast-growth
On HRT
- Information on Estrogen Hormone Therapy | Gender Affirming Health Program
- Injections - HRT Cafe
- Hormone therapy for transgender patients - PMC
- Testosterone Blockers for Transgender Women
- Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss - PMC
- Gender-Affirming Hormone Therapy: Physical and Sociopsychological Effects, Impact and Satisfaction - PMC
- This one is important when your lab insists on interpreting any of your results according to your "Birth Sex." They need to read this: Approach to Interpreting Common Laboratory Pathology Tests in Transgender Individuals - PMC
On Endocrinology
- Review of adult gender transition medications: mechanisms, efficacy measures, and pharmacogenomic considerations - PMC
- Estrogens in Male Physiology | Physiological Reviews
- Roles of estrogens, estrogen-like compounds, and endocrine disruptors in adipocytes - PMC
- Molecular mechanism of estrogen–estrogen receptor signaling - PMC
- Estradiol - StatPearls - NCBI Bookshelf
- Progesterone receptor in the prostate: A potential suppressor for benign prostatic hyperplasia and prostate cancer - PubMed
- Relationship Between Serum Estradiol Concentrations and Clinical Outcomes in Transgender Individuals Undergoing Feminizing Hormone Therapy: A Narrative Review - PMC
- Estrogen Metabolism Pathway
- Position Statement: Challenges to the Measurement of Estradiol: An Endocrine Society Position Statement - PMC
- Hormonal Treatment of Transgender Women with Oral Estradiol - PMC
- Clinical pharmacokinetics and pharmacodynamics of finasteride - PubMed
- Hormonal Effects on Hair Follicles - PMC
- Progesterone in gender-affirming therapy of trans women - PMC
- Evidence for a Non-Genomic Action of Testosterone in Skeletal Muscle Which may Improve Athletic Performance: Implications for the Female Athlete - PMC
- Testosterone and Aggressive Behavior in Man - PMC
- Neurobiology of Aggressive Behavior—Role of Autoantibodies Reactive With Stress-Related Peptide Hormones - PMC
- Sex-specific Estrogen Levels and Reference Intervals from Infancy to Late Adulthood Determined by LC-MS/MS - PMC
- Progesterone Receptor Expression in the Benign Prostatic Hyperplasia and Prostate Cancer Tissues, Relation with Transcription, Growth Factors, Hormone Reception and Components of the AKT/mTOR Signaling Pathway - PMC